Functional MRI in Idiopathic Parkinson's Disease

被引：57

作者：

Filippi, Massimo ^{[1
,2
]}

Elisabetta, Sarasso ^{[1
,3
]}

Piramide, Noemi ^{[1
]}

Agosta, Federica ^{[1
]}

机构：

[1] Univ Vita Salute San Raffaele, Neuroimaging Res Unit, Inst Expt Neurol, Div Neurosci, Milan, Italy

[2] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Inst Expt Neurol, Dept Neurol,Div Neurosci, Milan, Italy

[3] Ist Sci San Raffaele, Lab Movement Anal, Milan, Italy

来源：

IMAGING IN MOVEMENT DISORDERS: IMAGING METHODOLOGY AND APPLICATIONS IN PARKINSON'S DISEASE | 2018年 / 141卷

关键词：

DEFAULT-MODE NETWORK; MILD COGNITIVE IMPAIRMENT; DRUG-NAIVE PATIENTS; IMPULSE CONTROL DISORDERS; RESTING-STATE; BASAL GANGLIA; REGIONAL HOMOGENEITY; BRAIN CONNECTIVITY; WORKING-MEMORY; DUAL TASKING;

D O I：

10.1016/bs.irn.2018.08.005

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Functional MRI (fMRI) has been widely used to study abnormal patterns of brain connectivity at rest and activation during a variety of tasks in patients with idiopathic Parkinson's disease (PD). fMRI studies in PD have led to a better understanding of many aspects of the disease including both motor and non-motor symptoms. Although its translation into clinical practice is still at an early stage, fMRI measures hold promise for multiple clinical applications in PD, including the early detection, predicting future change in clinical status, and as a marker of alterations in brain physiology related to neurotherapeutic agents and neurorehabilitative strategies.

引用

页码：439 / 467

页数：29

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