Cytoplasmic dynein could be key to understanding neurodegeneration

被引：26

作者：

Banks, Gareth T. ^{[1
]}

Fisher, Elizabeth M. C. ^{[1
]}

机构：

[1] Inst Neurol, Dept Neurodegenerat Dis, London WC1N 3BG, England

来源：

GENOME BIOLOGY | 2008年 / 9卷 / 03期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1186/gb-2008-9-3-214

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new mouse mutation, Sprawling, highlights an essential role for the dynein heavy chain in sensory neuron function, but it lacks the ability of other known heavy-chain mutations to ameliorate neurodegeneration due to defective superoxide dismutase.

引用

页数：4

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