Dioxygen-coupled oxidative amination of styrene

被引：138

作者：

Timokhin, VI ^{[1
]}

Anastasi, NR ^{[1
]}

Stahl, SS ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 43期

关键词：

D O I：

10.1021/ja0362149

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dioxygen-coupled oxidative amination of olefins is an attractive, but challenging, catalytic transformation. The present work describes the first general method for intermolecular oxidative amination of aryl olefins with molecular oxygen as the stoichiometric oxidant. This palladium-catalyzed reactivity is compatible with several different nitrogen nucleophiles, including oxazolidinone, phthalimide, pyrrolidinone, and p-toluenesulfonamide. The presence of a catalytic quantity of a Brønsted base in the reaction increases the catalytic activity and switches the reaction regioselectivity. Copyright © 2003 American Chemical Society.

引用

页码：12996 / 12997

页数：2

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