InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar typhimurium

被引:46
作者
Ehrbar, K [1 ]
Hapfelmeier, S [1 ]
Stecher, B [1 ]
Hardt, WD [1 ]
机构
[1] ETH, Inst Microbiol, CH-8092 Zurich, Switzerland
关键词
D O I
10.1128/JB.186.4.1215-1219.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA and slightly stabilizes it in the bacterial cytosol and that it is required for its transport via the SPI-1 TTSS.
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页码:1215 / 1219
页数:5
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