Immunotoxins and other conjugates: Pre-clinical studies

被引：51

作者：

Bolognesi, A ^{[1
]}

Polito, L ^{[1
]}

机构：

[1] Univ Bologna, Dept Expt Pathol, I-40126 Bologna, Italy

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2004年 / 4卷 / 05期

关键词：

ribosome-inactivating proteins; toxins; conjugates; immunotoxins; targeting; immunotherapy;

D O I：

10.2174/1389557043403864

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.

引用

页码：563 / 583

页数：21

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