Mechanically stable implants of synthetic bone mineral by cold isostatic pressing

被引:50
作者
Tadic, D [1 ]
Epple, M [1 ]
机构
[1] Ruhr Univ Bochum, Fac Chem, D-44780 Bochum, Germany
关键词
calcium phosphates; cold isostatic pressing; bone substitution materials; mechanical stability; porosity;
D O I
10.1016/S0142-9612(03)00281-3
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A calcium phosphate phase that is equivalent in composition (carbonate content) and crystallinity (nanocrystals) to the mineral phase of bone was prepared by a continuous precipitation method. The powder was compacted by cold isostatic pressing into desired shapes with high compressive strength (range of 20-50 MPa, depending on the geometry). It is concluded that such implant materials can be prepared with a fine-tuned biodegradability in combination with a high mechanical strength. The high mechanical strength of the objects also permits further mechanical shaping procedures like drilling or cutting. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4565 / 4571
页数:7
相关论文
共 46 条
[41]  
2-A
[42]  
Willmann G, 1999, ADV ENG MATER, V1, P95
[43]   Histology of human alveolar bone regeneration with a porous tricalcium phosphate - A report of two cases [J].
Zerbo, IR ;
Bronckers, ALJJ ;
de Lange, GL ;
van Beek, GJ ;
Burger, EH .
CLINICAL ORAL IMPLANTS RESEARCH, 2001, 12 (04) :379-384
[44]  
Zyman Z, 2001, J BIOMED MATER RES, V54, P256, DOI 10.1002/1097-4636(200102)54:2<256::AID-JBM13>3.0.CO
[45]  
2-B
[46]   Elastic modulus and hardness of cortical and trabecular bone lamellae measured by nanoindentation in the human femur [J].
Zysset, PK ;
Guo, XE ;
Hoffler, CE ;
Moore, KE ;
Goldstein, SA .
JOURNAL OF BIOMECHANICS, 1999, 32 (10) :1005-1012