Formate and its role in hydrogen production in Escherichia coli

被引：166

作者：

Sawers, RG ^{[1
]}

机构：

[1] John Innes Inst, Dept Mol Microbiol, Norwich NR4 7UH, Norfolk, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2005年 / 33卷

关键词：

formate dehydrogenase; formate hydrogenlyase; formate regulon; formic acid; NiFe-hydrogenase; pyruvate formate-lyase;

D O I：

10.1042/BST0330042

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The production of dihydrogen by Escherichia coli and other members of the Enterobacteriaceae is one of the classic features of mixed-acid fermentation. Synthesis of the multicomponent, membrane-associated FHL (formate hydrogenlyase) enzyme complex, which disproportionates formate into CO2 and H-2, has an absolute requirement for formate. Formate, therefore, represents a signature molecule in the fermenting E. coli cell and factors that determine formate metabolism control FHL synthesis and consequently dihydrogen evolution.

引用

页码：42 / 46

页数：5

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