The Homeodomain Resource: sequences, structures, DNA binding sites and genomic information

被引:16
作者
Banerjee-Basu, S [1 ]
Sink, DW [1 ]
Baxevanis, AD [1 ]
机构
[1] NHGRI, Genome Technol Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1093/nar/29.1.291
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Homeodomain Resource is an annotated collection of non-redundant protein sequences, three-dimensional structures and genomic information for the homeodomain protein family. Release 3.0 contains 795 full-length homeodomain-containing sequences, 32 experimental ly-derived structures and 143 homeobox loci implicated in human genetic disorders. Entries are fully hyperlinked to facilitate easy retrieval of the original records from source databases. A simple search engine with a graphical user interface is provided to query the component databases and assemble customized data sets. A new feature for this release is the addition of DNA recognition sites for all human homeodomain proteins described in the literature. The Homeodomain Resource is freely available through the World Wide Web at http:// genome.nhgri.nih.gov/homeodomain.
引用
收藏
页码:291 / 293
页数:3
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