Intramolecular Heck reactions of unactivated alkyl halides

被引：203

作者：

Firmansjah, Luke ^{[1
]}

Fu, Gregory C. ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 37期

关键词：

D O I：

10.1021/ja075245r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method has been developed for achieving palladium-catalyzed intramolecular Heck reactions of unactivated, beta-hydrogen-containing alkyl bromides and chlorides. The data from a stereochemical investigation are consistent with carbon-carbon bond formation via an alkylpalladium, rather than a radical, intermediate.

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页码：11340 / +

页数：3

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