Is insulin an antiinflammatory molecule?

被引:130
作者
Das, UN [1 ]
机构
[1] EFA Sci LLC, Norwood, MA 02062 USA
关键词
insulin; tumor necrosis factor; inflammation; macrophage migration inhibitory factor; diabetes mellitus;
D O I
10.1016/S0899-9007(01)00518-4
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
I suggest that insulin suppresses the secretion and antagonizes the harmful effects of tumor necrosis factor-alpha, macrophage migration-inhibitory factor, and superoxide anion. Therefore, the glucose-insulin-potassium regimen might be beneficial in acute myocardial infarction and useful in the management of patients with septicemia, septic shock, and other inflammatory diseases in which tumor necrosis factor-a and macrophage migration-inhibitory factor have important roles.
引用
收藏
页码:409 / 413
页数:5
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