Successful cidofovir treatment of adenovirus-associated hemorrhagic cystitis and renal dysfunction after allogeneic bone marrow transplantation

被引:46
作者
Hatakeyama, N [1 ]
Suzuki, N [1 ]
Kudoh, T [1 ]
Hori, T [1 ]
Mizue, N [1 ]
Tsutsumi, H [1 ]
机构
[1] Sapporo Med Univ, Sch Med, Dept Pediat, Chuo Ku, Sapporo, Hokkaido 0608543, Japan
关键词
hemorrhagic cystitis; BK virus; adenovirus; bone marrow transplantation; cidofovir;
D O I
10.1097/01.inf.0000091399.29505.21
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We present a patient who developed hemorrhagic cystitis and renal dysfunction after unrelated bone marrow transplantation. Polyoma BK virus and adenovirus type 11 were detected in the urine. Vidarabine was administered without effect. Relatively low dose cidofovir was efficacious. Renal function improved, and the urinary excretion of adenovirus stopped.
引用
收藏
页码:928 / 929
页数:2
相关论文
共 19 条
[11]   Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation [J].
Hoffman, JA ;
Shah, AJ ;
Ross, LA ;
Kapoor, N .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2001, 7 (07) :388-394
[12]  
JURADO M, 1995, BONE MARROW TRANSPL, V15, P651
[13]   Vidarabine therapy for virus-associated cystitis after allogeneic bone marrow transplantation [J].
Kawakami, M ;
Ueda, S ;
Maeda, T ;
Karasuno, T ;
Teshima, H ;
Hiraoka, A ;
Nakamura, H ;
Tanaka, K ;
Masaoka, T .
BONE MARROW TRANSPLANTATION, 1997, 20 (06) :485-490
[14]  
KITABAYASHI A, 1994, BONE MARROW TRANSPL, V14, P853
[15]   Adenovirus infections in adult recipients of blood and marrow transplants [J].
La Rosa, AM ;
Champlin, RE ;
Mirza, N ;
Gajewski, J ;
Giralt, S ;
Rolston, KV ;
Raad, I ;
Jacobson, K ;
Kontoyiannis, D ;
Elting, L ;
Whimbey, E .
CLINICAL INFECTIOUS DISEASES, 2001, 32 (06) :871-876
[16]   Early diagnosis of adenovirus infection and treatment with cidofovir after bone marrow transplantation in children [J].
Legrand, F ;
Berrebi, D ;
Houhou, N ;
Freymuth, F ;
Faye, A ;
Duval, M ;
Mougenot, JF ;
Peuchmaur, M ;
Vilmer, E .
BONE MARROW TRANSPLANTATION, 2001, 27 (06) :621-626
[17]   Successful ribavirin therapy for severe adenovirus hemorrhagic cystitis after allogeneic marrow transplant from close HLA donors rather than distant donors [J].
Miyamura, K ;
Hamaguchi, M ;
Taji, H ;
Kanie, T ;
Kohno, A ;
Tanimoto, M ;
Saito, H ;
Kojima, S ;
Matsuyama, T ;
Kitaori, K ;
Nagafuji, K ;
Sato, T ;
Kodera, Y .
BONE MARROW TRANSPLANTATION, 2000, 25 (05) :545-548
[18]  
MIYAMURA K, 1989, BONE MARROW TRANSPL, V4, P533
[19]   Sequential vidarabine infusion in the treatment of polyoma virus-associated acute haemorrhagic cystitis late after allogeneic bone marrow transplantation [J].
Vianelli, N ;
Renga, M ;
Azzi, A ;
De Santis, R ;
Bandini, G ;
Tosi, P ;
Tura, S .
BONE MARROW TRANSPLANTATION, 2000, 25 (03) :319-320