Novel 6,12-disubstituted chrysene as potent anticancer agent: Synthesis, in vitro and in vivo study

被引：26

作者：

Banik, Bimal K. ^{[1
]}

Becker, Frederick F. ^{[2
]}

机构：

[1] Univ Texas Pan Amer, Dept Chem, Edinburg, TX 78539 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Mol Pathol, Unit 951, Houston, TX 77030 USA

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2010年 / 45卷 / 10期

关键词：

Substituted chrysenes; Anticancer agents; In vitro assay; In vivo test; POLYCYCLIC AROMATIC-COMPOUNDS; ANTITUMOR-ACTIVITY; BIOLOGICAL EVALUATION; DNA INTERCALATORS; ANTHRACENE-9,10-DIONES; DERIVATIVES; REDUCTION; BINDING; IMINES;

D O I：

10.1016/j.ejmech.2010.07.033

中图分类号：

R914 [药物化学];

学科分类号：

100705 [微生物与生化药学];

摘要：

引用

页码：4687 / 4691

页数：5

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