Synthesis of (R)-cyanohydrins by crude (R)-oxynitrilase-catalyzed reactions in micro-aqueous medium

被引:51
作者
Han, SQ [1 ]
Lin, GQ [1 ]
Li, ZY [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1016/S0957-4166(98)00177-3
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
In diisopropyl ether or ethyl acetate under micro-aqueous conditions, the enantioselective synthesis of (R) cyanohydrins from aldehydes and methyl ketones was studied using crude (R)-oxynitrilase prepared from almonds. This reaction system performed well over the temperature range of 4 degrees C to 30 degrees C. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1835 / 1838
页数:4
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