Dendritic arbor development and synaptogenesis

被引:407
作者
Cline, HT [1 ]
机构
[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
D O I
10.1016/S0959-4388(00)00182-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In vivo studies indicate that synaptic activity promotes dendritic arbor elaboration at early stages of brain development. At later stages of development, synaptic activity stabilizes dendritic structure. The different roles of synaptic activity with respect to structural plasticity probably reflect the regulated spatiotemporal expression of key components within signaling pathways.
引用
收藏
页码:118 / 126
页数:9
相关论文
共 61 条
[11]  
Fiala JC, 1998, J NEUROSCI, V18, P8900
[12]   Genes regulating dendritic outgrowth, branching, and routing in Drosophila [J].
Gao, FB ;
Brenman, JE ;
Jan, LY ;
Jan, YN .
GENES & DEVELOPMENT, 1999, 13 (19) :2549-2561
[13]   Requirement for alpha-CaMKII in experience-dependent plasticity of the barrel cortex [J].
Glazewski, S ;
Chen, CM ;
Silva, A ;
Fox, K .
SCIENCE, 1996, 272 (5260) :421-423
[14]   Deficient plasticity in the primary visual cortex of alpha-calcium/calmodulin-dependent protein kinase II mutant mice [J].
Gordon, JA ;
Cioffi, D ;
Silva, AJ ;
Stryker, MP .
NEURON, 1996, 17 (03) :491-499
[15]   DENDRITIC PATTERN-FORMATION INVOLVES BOTH ORIENTED REGRESSION AND ORIENTED GROWTH IN THE BARRELS OF MOUSE SOMATOSENSORY CORTEX [J].
GREENOUGH, WT ;
CHANG, FLF .
DEVELOPMENTAL BRAIN RESEARCH, 1988, 43 (01) :148-152
[16]  
HAAS H, 2001, IN PRESS NEURON
[17]   Rho GTPases and the actin cytoskeleton [J].
Hall, A .
SCIENCE, 1998, 279 (5350) :509-514
[18]   Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction [J].
Hayashi, Y ;
Shi, SH ;
Esteban, JA ;
Piccini, A ;
Poncer, JC ;
Malinow, R .
SCIENCE, 2000, 287 (5461) :2262-2267
[19]   Experience-dependent development of spinal motor neurons [J].
Inglis, FM ;
Zuckerman, KE ;
Kalb, RG .
NEURON, 2000, 26 (02) :299-305
[20]   Silent glutamatergic synapses in the mammalian brain [J].
Isaac, JTR ;
Nicoll, RA ;
Malenka, RC .
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1999, 77 (09) :735-737