Is otitis media with effusion a biofilm infection?

被引：53

作者：

Fergie, N ^{[1
]}

Bayston, R

Pearson, JP

Birchall, JP

机构：

[1] Queens Med Ctr, Dept Otolaryngol & Head & Neck Surg, Nottingham NG7 2UH, England

[2] Univ Nottingham, Sch Med & Surg Sci, Biomat Related Infect Grp, Nottingham NG7 2RD, England

[3] Newcastle Univ, Dept Physiol, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

CLINICAL OTOLARYNGOLOGY | 2004年 / 29卷 / 01期

关键词：

small colony variants; biofilms; otitis media;

D O I：

10.1111/j.1365-2273.2004.00767.x

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Recent attention has focused on the possibility that otitis media with effusion (OME) may represent a chronic infective state such as those evidenced in conditions secondary to biofilms or small colony variants. This review discusses the evidence suggesting that this may indeed be the case and explains why this may prove to be important in the future management of this condition by discussing recent advances in understanding these bacterial phenotypic variants.

引用

页码：38 / 46

页数：9

共 100 条

[71] CLINICAL ISOLATION AND CHARACTERIZATION OF AMINOGLYCOSIDE-RESISTANT SMALL COLONY VARIANTS OF ENTEROBACTER AEROGENES [J].

RUSTHOVEN, JJ ;

DAVIES, TA ;

LERNER, SA .

AMERICAN JOURNAL OF MEDICINE, 1979, 67 (04) :702-706

[72]

Sakito O, 1996, RESPIRATION, V63, P42

[73] USE OF A SHORT COURSE OF PREDNISONE FOR TREATING MIDDLE-EAR EFFUSION - A DOUBLE-BLIND CROSSOVER STUDY [J].

SCHWARTZ, RH ;

PUGLESE, J ;

SCHWARTZ, DM .

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1980, 89 (03) :296-300

[74] Thinking about bacterial populations as multicellular organisms [J].

Shapiro, JA .

ANNUAL REVIEW OF MICROBIOLOGY, 1998, 52 :81-104

[75] Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms [J].

Singh, PK ;

Schaefer, AL ;

Parsek, MR ;

Moninger, TO ;

Welsh, MJ ;

Greenberg, EP .

NATURE, 2000, 407 (6805) :762-764

[76]

Sternberg C, 1999, APPL ENVIRON MICROB, V65, P4108

[77] INVESTIGATION OF CIPROFLOXACIN PENETRATION INTO PSEUDOMONAS-AERUGINOSA BIOFILMS [J].

SUCI, PA ;

MITTELMAN, MW ;

YU, FP ;

GEESEY, GG .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (09) :2125-2133

[78] The biofilm matrix - an immobilized but dynamic microbial environment [J].

Sutherland, IW .

TRENDS IN MICROBIOLOGY, 2001, 9 (05) :222-227

[79]

TUOMANEN E, 1986, J GEN MICROBIOL, V132, P1297

[80] ANTIBIOTIC TOLERANCE AMONG CLINICAL ISOLATES OF BACTERIA [J].

TUOMANEN, E ;

DURACK, DT ;

TOMASZ, A .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 30 (04) :521-527

← 1 2 3 4 5 6 7 8 9 10 →