Efficient asymmetric protonation of enolates with readily accessible chiral α-sulfinyl alcohols

被引：27

作者：

Asensio, G ^{[1
]}

Alemán, P ^{[1
]}

Cuenca, A ^{[1
]}

Gil, J ^{[1
]}

Medio-Simón, M ^{[1
]}

机构：

[1] Univ Valencia, Dept Quim Organ, E-46100 Burjassot, Spain

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 22期

关键词：

D O I：

10.1016/S0957-4166(98)00426-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The efficient asymmetric protonation of lithium enolates of 2-alkylcycloalkanones (87-96% ee) with readily accessible chiral alpha-sulfinyl alcohols is described. Optimal stereoselection is achieved for each lithium enolate at a different reaction temperature in the range -40 to - 100 degrees C. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4073 / 4078

页数：6

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