PrDOS: prediction of disordered protein regions from amino acid sequence

被引:631
作者
Ishida, Takashi [1 ]
Kinoshita, Kengo [1 ,2 ]
机构
[1] Univ Tokyo, Inst Med Sci, Minato Ku, Tokyo 1088639, Japan
[2] SORST JST, Kawaguchi, Saitama 3320012, Japan
基金
日本科学技术振兴机构;
关键词
D O I
10.1093/nar/gkm363
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
PrDOS is a server that predicts the disordered regions of a protein from its amino acid sequence (http://prdos.hgc.jp). The server accepts a single protein amino acid sequence, in either plain text or FASTA format. The prediction system is composed of two predictors: a predictor based on local amino acid sequence information and one based on template proteins. The server combines the results of the two predictors and returns a two-state prediction (order/disorder) and a disorder probability for each residue. The prediction results are sent by e-mail, and the server also provides a web-interface to check the results.
引用
收藏
页码:W460 / W464
页数:5
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