Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source

被引:148
作者
Choma, MA
Hsu, K
Izatt, JA
机构
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
[2] Micron Opt Inc, Atlanta, GA 30345 USA
关键词
optical coherence tomography; medical imaging; biological imaging; tunable lasers; ophthalmic imaging; skin imaging;
D O I
10.1117/1.1961474
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The increased sensitivity of spectral domain optical coherence tomography (OCT) has driven the development of a new generation of technologies in OCT, including rapidly tunable, broad bandwidth swept laser sources and spectral domain OCT interferometer topologies. In this work, the operation of a turnkey 1300-nm swept laser source is demonstrated. This source has a fiber ring cavity with a semiconductor optical amplifier gain medium. Intracavity mode selection is achieved with an in-fiber tunable fiber Fabry-Perot filter. A novel optoelectronic technique that allows for even sampling of the swept source OCT signal in k space also is described. A differential swept source OCT system is presented, and images of in vivo human cornea and skin are presented. Lastly, the effects of analog-to-digital converter aliasing on image quality in swept source OCT are discussed. (C) 2005 Society of Photo-Optical Instrumentation Engineers.
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页数:6
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