Phase-specific modulation of cortical motor output during movement observation

被引：329

作者：

Gangitano, M ^{[1
]}

Mottaghy, FM ^{[1
]}

Pascual-Leone, A ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr,Dept Neurol, Div Behav Neurol,Lab Magnet Brain Stimulat, Boston, MA 02215 USA

来源：

NEUROREPORT | 2001年 / 12卷 / 07期

关键词：

mirror neurons; premotor cortex; transcranial magnetic stimulation;

D O I：

10.1097/00001756-200105250-00038

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

The effects of different phases of an observed movement on the modulation of cortical motor output were studied by means of transcranial magnetic stimulation (TMS). A video-clip of a reaching-grasping action was shown and single TMS pulses were delivered during its passive observation. Times of cortical stimulation were related to the phases of the shown movement, locking them to the appearance of specific kinematic landmarks. The amplitude of the motor evoked potentials (MEPs) induced by TMS in the first dorsal interosseus (FDI) muscle was modulated by the amount of the observed finger aperture. The presence of such an effect is consistent with the notion of a mirror neuron system in premotor areas that couples action execution and action observation also in terms of temporal coding. NeuroReport 12:1489-1492 (C) 2001 Lippincott Williams & Wilkins.

引用

页码：1489 / 1492

页数：4

共 19 条

[1]

Modulation of spinal excitability during observation of hand actions in humans [J].