Toxicological Responses of Cyprinus carpio Exposed to a Commercial Formulation Containing Glyphosate

被引：75

作者：

Cattaneo, Roberta ^{[2
]}

Clasen, Barbara ^{[2
]}

Loro, Vania Lucia ^{[1
]}

de Menezes, Charlene Cavalheiro ^{[2
]}

Pretto, Alexandra ^{[2
]}

Baldisserotto, Bernardo ^{[3
]}

Santi, Adriana ^{[2
]}

de Avila, Luis Antonio ^{[4
]}

机构：

[1] Univ Fed Santa Maria UFSM, Dept Quim, Ctr Ciencias Nat & Exatas, BR-97105900 Santa Maria, RS, Brazil

[2] Univ Fed Santa Maria, Programa Posgrad Bioquim Toxicol, BR-97105900 Santa Maria, RS, Brazil

[3] Univ Fed Santa Maria UFSM, Dept Fisiol, Ctr Ciencias Saude, BR-97105900 Santa Maria, RS, Brazil

[4] Univ Fed Pelotas UFPel, Dept Fitossanidade, Pelotas, RS, Brazil

来源：

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2011年 / 87卷 / 06期

关键词：

Glyphosate; Carp; AChE; TBARS; CATFISH RHAMDIA-QUELEN; ACETYLCHOLINESTERASE ACTIVITY; HERBICIDE GLYPHOSATE; CLOMAZONE HERBICIDE; FISH; TOXICITY; RECOVERY; BRAIN; LIVER; PARAMETERS;

D O I：

10.1007/s00128-011-0396-7

中图分类号：

X [环境科学、安全科学];

学科分类号：

083001 [环境科学];

摘要：

The effects of commercial glyphosate herbicide formulation on the activity of acetylcholinesterase (AChE) enzyme and oxidative stress were studied in Cyprinus carpio exposed for 96 h to 0.0, 0.5, 2.5, 5.0 and 10.0 mg/L and then allowed to equal recovery period in water without herbicide. The activity of AChE was inhibited in the brain and in the muscle after exposure. However, after recovery period brain and muscle AChE activity increased. Brain thiobarbituric acid reactive species (TBARS) were measured as an indicator of oxidative stress. Increased TBARS levels were observed with all concentrations tested of the glyphosate formulation, and remained increased after the recovery period. The results recorded clearly indicate lipid peroxidation and anti-AChE action induced by Roundup(A (R)) exposure.

引用

页码：597 / 602

页数：6

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