Microfluidic Platform for the Study of Caenorhabditis elegans

被引:26
作者
Shi, Weiwei [1 ]
Wen, Hui [1 ]
Lin, Bingcheng [1 ]
Qin, Jianhua [1 ]
机构
[1] Chinese Acad Sci, Dalian Inst Chem & Phys, Dalian 116023, Peoples R China
来源
MICROFLUIDICS: TECHNOLOGIES AND APPLICATIONS | 2011年 / 304卷
基金
中国国家自然科学基金;
关键词
Caenorhabditis elegans; Microfluidics; Neurobiology; Neuron degeneration; Neuron regeneration; FUNCTIONAL GENOMIC ANALYSIS; C-ELEGANS; OLFACTORY BEHAVIOR; NEMATODE; SYSTEM; CHIP; IMMOBILIZATION; ELECTROTAXIS; NEUROBIOLOGY; LOCOMOTION;
D O I
10.1007/128_2011_145
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Caenorhabditis elegans is a well-established model organism for the study of various biological areas. However, the procedures generally used for this worm are limited by the low throughput, low automation, and imprecise delivery of external stimuli. Microfluidics technology is emerging as an attractive and enabling platform to overcome these problems. In this review, we summarize the current microfluidic approaches for the investigation of behavior and neurobiology in C. elegans, and discuss the trends of future development.
引用
收藏
页码:323 / 338
页数:16
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