Relationship between antimutagenic activity and major components of various teas

被引:76
作者
Yen, GC
Chen, HY
机构
[1] Department of Food Science, National Chung Hsing University, Taichung
关键词
D O I
10.1093/mutage/11.1.37
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The objectives of this study were to determine the major components in tea leaves and tea extracts and to study the relationship between chemical content and antimutagenic activity of various tea extracts, The amount of catechins in various tea extracts was in the order: green tea (26.7%) > oolong tea (23.2%) > pouchong tea (15.8%) > black tea (4.3%). The amounts of caffeine and phenolic compounds in oolong tea extracts were 8.3 and 32.4%, respectively; these amounts were greater than those in the other three tea extracts, The ascorbic acid in green tea extracts was a little higher than in oolong and pouchong tea extracts, The amount of catechins in tea leaves also showed the order: nonfermented (green tea) > semifermented (pouchong tea and oolong tea) > fermented tea (black tea). The amounts of caffeine and phenolic compounds in oolong tea leaves are also higher than in other tea leaves. Besides water soluble components, tea leaves also contain several lipid soluble chemicals such as beta-carotene and tocopherols, The tea extracts, especially oolong and pouchong teas, markedly inhibited the mutagenicity of 2-amino-3-methylimidazo(4,5-f)quinoline (IQ), 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole (Trp-P-1), 2-amino-6-methyl-dipyrido(1,2-a:3',2'-d)imidazole (Glu-P-1), benzo[a]pyrene (B[a]P) and aflatoxin B-1 (AFB(1)). The inhibitory effect of tea extracts against the mutagenicity of IQ and Glu-P-1 in Salmonella typhimurium TA100 showed a significant (P < 0.05) correlation to the contents of catechins and ascorbic acid, The antimutagenic activity of tea extracts to Trp-P-1 in TA98 or TA100 was well correlated (P < 0.05) to the caffeine contents, No significant (P > 0.05) correlation was found between the antimutagenicity of tea extracts to B[a]P and AFB(1) in TA100 and the content of major components in tea extracts.
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页码:37 / 41
页数:5
相关论文
共 33 条
[1]   DETERMINATION OF TOCOPHEROLS IN VEGETABLE-OILS [J].
CARPENTER, AP .
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1979, 56 (07) :668-671
[2]   MULTIPLE RANGE AND MULTIPLE F TESTS [J].
DUNCAN, DB .
BIOMETRICS, 1955, 11 (01) :1-42
[3]   GREEN TEA COMPOSITION, CONSUMPTION, AND POLYPHENOL CHEMISTRY [J].
GRAHAM, HN .
PREVENTIVE MEDICINE, 1992, 21 (03) :334-350
[4]   METABOLIC ACTIVATION OF AFLATOXINS RELATED TO THEIR MUTAGENICITY [J].
GURTOO, HL ;
DAHMS, RP ;
PAIGEN, B .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 81 (03) :965-972
[5]  
HASHIMOTO F, 1989, CHEM PHARM BULL, V37, P3255
[6]  
HASHIMOTO F, 1988, CHEM PHARM BULL, V36, P1676
[7]   METABOLIC-ACTIVATION OF A MUTAGEN, 2-AMINO-6-METHYLDIPYRIDO-[1,2-A, 3',2'-D]IMIDAZOLE - IDENTIFICATION OF 2-HYDROXYAMINO-6-METHYLDIPYRIDO[1,2-A, 3',2'-D]IMIDAZOLE AND ITS REACTION WITH DNA [J].
HASHIMOTO, Y ;
SHUDO, K ;
OKAMOTO, T .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 92 (03) :971-976
[8]   SOME STUDIES ON CAROTENOIDS AND THEIR DEGRADATION IN BLACK TEA MANUFACTURE [J].
HAZARIKA, M ;
MAHANTA, PK .
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 1983, 34 (12) :1390-1396
[9]  
HIROSHI K, 1990, FRAGRANCE J, V11, P71
[10]   DETECTION AND CHEMICAL-IDENTIFICATION OF NATURAL BIO-ANTIMUTAGENS - A CASE OF THE GREEN TEA FACTOR [J].
KADA, T ;
KANEKO, K ;
MATSUZAKI, S ;
MATSUZAKI, T ;
HARA, Y .
MUTATION RESEARCH, 1985, 150 (1-2) :127-132