Stem Cells

被引：46

作者：

Behr, Bjorn ^{[1
]}

Ko, Sae Hee

Wong, Victor W.

Gurtner, Geoffrey C.

Longaker, Michael T.

机构：

[1] Stanford Univ, Sch Med, Dept Surg,Div Plast & Reconstruct Surg, Hagey Lab Regenerat Med, Stanford, CA USA

[2] Stanford Univ, Sch Med, Inst Stem Cell Biol & Regenerat Med, Stanford, CA USA

[3] Heidelberg Univ, BG Unfallklin Ludwigshafen, Dept Plast & Hand Surg, Heidelberg, Germany

来源：

PLASTIC AND RECONSTRUCTIVE SURGERY | 2010年 / 126卷 / 04期

关键词：

HUMAN ADIPOSE-TISSUE; THERAPY POSITION STATEMENT; UMBILICAL-CORD BLOOD; ADULT SOMATIC-CELLS; STROMAL CELLS; BONE-MARROW; NUCLEAR TRANSFER; REGENERATIVE MEDICINE; INTERNATIONAL-SOCIETY; CALVARIAL DEFECTS;

D O I：

10.1097/PRS.0b013e3181ea42bb

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

Summary: Stem cells are self-renewing cells capable of differentiating into multiple cell lines and are classified according to their origin and their ability to differentiate. Enormous potential exists in use of stem cells for regenerative medicine. To produce effective stem cell-based treatments for a range of diseases, an improved understanding of stem cell biology and better control over stem cell fate are necessary. In addition, the barriers to clinical translation, such as potential oncologic properties of stem cells, need to be addressed. With renewed government support and continued refinement of current stem cell methodologies, the future of stem cell research is exciting and promises to provide novel reconstructive options for patients and surgeons limited by traditional paradigms.

引用

收藏

页码：1163 / 1171

页数：9

相关论文

共 65 条

[1]

Liver stem cells: a two compartment system [J].

Alison, M .

CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (06) :710-715

[2]

Induced pluripotent stem cells: current progress and potential for regenerative medicine [J].

Amabile, Giovanni ;

Meissner, Alexander .

TRENDS IN MOLECULAR MEDICINE, 2009, 15 (02) :59-68

[3]

In vitro cultivation of human islets from expanded ductal tissue [J].

Bonner-Weir, S ;

Taneja, M ;

Weir, GC ;

Tatarkiewicz, K ;

Song, KH ;

Sharma, A ;

O'Neil, JJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (14) :7999-8004

[4]

Producing primate embryonic stem cells by somatic cell nuclear transfer [J].

Byrne, J. A. ;

Pedersen, D. A. ;

Clepper, L. L. ;

Nelson, M. ;

Sanger, W. G. ;

Gokhale, S. ;

Wolf, D. P. ;

Mitalipov, S. M. .

NATURE, 2007, 450 (7169) :497-U3

[5]

Adipogenic differentiation of adipose tissue derived adult stem cells in nude mouse [J].

Choi, Yu Suk ;

Cha, Sang Myun ;

Lee, Young Yeol ;

Kwon, Seok Woon ;

Park, Chan Jeoung ;

Kim, MiJung .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2006, 345 (02) :631-637

[6]

Stem cells: Promises versus limitations [J].

Choumerianou, Despoina M. ;

Dimitriou, Helen ;

Kalmanti, Maria .

TISSUE ENGINEERING PART B-REVIEWS, 2008, 14 (01) :53-60

[7]

Adipose-derived adult stromal cells heal critical-size mouse calvarial defects [J].

Cowan, CM ;

Shi, YY ;

Aalami, OO ;

Chou, YF ;

Mari, C ;

Thomas, R ;

Quarto, N ;

Contag, CH ;

Wu, B ;

Longaker, MT .

NATURE BIOTECHNOLOGY, 2004, 22 (05) :560-567

[8]

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons [J].

Dimos, John T. ;

Rodolfa, Kit T. ;

Niakan, Kathy K. ;

Weisenthal, Laurin M. ;

Mitsumoto, Hiroshi ;

Chung, Wendy ;

Croft, Gist F. ;

Saphier, Genevieve ;

Leibel, Rudy ;

Goland, Robin ;

Wichterle, Hynek ;

Henderson, Christopher E. ;

Eggan, Kevin .

SCIENCE, 2008, 321 (5893) :1218-1221

[9]

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement [J].

Dominici, M. ;

Le Blanc, K. ;

Mueller, I. ;

Slaper-Cortenbach, I. ;

Marini, F. C. ;

Krause, D. S. ;

Deans, R. J. ;

Keating, A. ;

Prockop, D. J. ;

Horwitz, E. M. .

CYTOTHERAPY, 2006, 8 (04) :315-317

[10]

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation [J].

Dor, Y ;

Brown, J ;

Martinez, OI ;

Melton, DA .

NATURE, 2004, 429 (6987) :41-46

← 1 2 3 4 5 6 7 →