Clonal identification of Burkitt's lymphoma arising from lymphocyte-predominant Hodgkin's disease

被引：13

作者：

Yoshinaga, H

Ohashi, K

Yamamoto, K

Miki, T

Miura, O

Saito, T

Koyama, T

Kanazawa, A

Nemoto, T

Miyasaka, N

Kamiyama, R

Hirosawa, S

机构：

[1] TOKYO MED & DENT UNIV,DEPT INTERNAL MED 1,FAC MED,BUNKYO KU,TOKYO 113,JAPAN

[2] TOKYO MED & DENT UNIV,SCH ALLIED HLTH SCI,FAC MED,BUNKYO KU,TOKYO 113,JAPAN

[3] TOKYO MED & DENT UNIV,DEPT PATHOL & IMMUNOL,FAC MED,BUNKYO KU,TOKYO 113,JAPAN

[4] TOKYO MED & DENT UNIV,DEPT PATHOL,FAC MED,BUNKYO KU,TOKYO 113,JAPAN

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1996年 / 95卷 / 02期

关键词：

Burkitt's lymphoma; Hodgkin's disease; clonality; polymerase chain reaction;

D O I：

10.1046/j.1365-2141.1996.d01-1914.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The occurrence of large cell lymphomas subsequent to, or concurrent with, lymphocyte predominant Hodgkin's disease (LPHD) is a well-documented phenomenon. We present a case of Burkitt's lymphoma of the bladder, occurring after the successful treatment of LPHD of a cervical lymph node. To evaluate the clonal relationship of the two tumours, we amplified the complementarity-determining-region 3 of two samples from paraffin-embedded slides, using the polymerase chain reaction (PCR). The sequences of the PCR products showed 96% homology to each other. These results indicate that the malignant clone of Burkitt's lymphoma arose from the corresponding LPHD.

引用

页码：380 / 382

页数：3

共 13 条

[1]

BRINKER MGL, 1987, BLOOD, V70, P186

[2] PROGRESSIVE TRANSFORMATION OF GERMINAL-CENTERS AND LYMPHOCYTE PREDOMINANT HODGKINS-DISEASE - THE STANFORD EXPERIENCE [J].