DNA is bound within the central hole to one or two of the six subunits of the T7 DNA helicase

被引：113

作者：

Yu, X

Hingorani, MM

Patel, SS

Egelman, EH

机构：

[1] UNIV MINNESOTA, SCH MED, DEPT CELL BIOL & NEUROANAT, MINNEAPOLIS, MN 55455 USA

[2] OHIO STATE UNIV, DEPT BIOCHEM, COLUMBUS, OH 43210 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1996年 / 3卷 / 09期

关键词：

D O I：

10.1038/nsb0996-740

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electron microscopic image analysis and protein-DNA crosslinking show that DNA binds asymmetrically to the hexameric bacteriophage T7 gp4b helicase, and binds to only one or two subunits.

引用

页码：740 / 743

页数：4

共 23 条

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CHEMICAL RESEARCH IN TOXICOLOGY, 1996, 9 (01) :179-187

[22] NUCLEOTIDE AND DNA-INDUCED CONFORMATIONAL-CHANGES IN THE BACTERIOPHAGE-T7 GENE-4-PROTEIN [J].

YONG, YQ ;

ROMANO, LJ .

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[23] The hexameric E-coli DnaB helicase can exist in different quarternary states [J].

Yu, X ;

Jezewska, MJ ;

Bujalowski, W ;

Egelman, EH .

JOURNAL OF MOLECULAR BIOLOGY, 1996, 259 (01) :7-14

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