Rate of Change in Kidney Function and the Risk of Death: The Case for Incorporating the Rate of Kidney Function Decline into the CKD Staging System

被引：7

作者：

Al-Aly, Ziyad ^{[1
,3
]}

Cepeda, Oscar ^{[2
]}

机构：

[1] St Louis Vet Affairs Med Ctr, Div Nephrol, St Louis, MO 63106 USA

[2] St Louis Vet Affairs Med Ctr, Div Hospitalist Med, St Louis, MO 63106 USA

[3] St Louis Vet Affairs Clin Res & Epidemiol Ctr, St Louis, MO USA

来源：

NEPHRON CLINICAL PRACTICE | 2011年 / 119卷 / 02期

关键词：

Chronic kidney disease; Rate of decline; Mortality; Progression; GLOMERULAR-FILTRATION-RATE; CARDIOVASCULAR-DISEASE; RENAL-INSUFFICIENCY; GENERAL-POPULATION; MORTALITY RISK; ALL-CAUSE; OUTCOMES; ALBUMINURIA; PREVALENCE; CALCIFICATION;

D O I：

10.1159/000324768

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic kidney disease (CKD) is associated with increased risk of death. A wave of recent studies used longitudinal data to examine the effect of the rate of decline of kidney function on the risk of death. The results from these studies show that there is an independent and graded association between the rate of kidney function decline and the risk of death. There is a need to incorporate the rate of decline in the definition of CKD. This redefinition of CKD will transform a static definition into a dynamic one that more accurately describes the disease state in an individual patient. Copyright (C) 2011 S. Karger AG, Basel

引用

页码：C179 / C185

页数：7

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