Purinergic Signaling in Healthy and Diseased Skin

被引：110

作者：

Burnstock, Geoffrey ^{[1
]}

Knight, Gillian E. ^{[1
]}

Greig, Aina V. H. ^{[2
]}

机构：

[1] Royal Free & Univ Coll Med Sch, Auton Neurosci Ctr, London NW3 2PF, England

[2] St Thomas Hosp, Dept Plast Surg, London, England

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2012年 / 132卷 / 03期

关键词：

TRIPHOSPHATE-MAGNESIUM CHLORIDE; ADENOSINE RECEPTOR ACTIVATION; EPIDERMAL LANGERHANS CELLS; CUTANEOUS SENSORY NEURONS; ENDOTHELIAL GROWTH-FACTOR; INDUCED CALCIUM-ENTRY; SMOOTH-MUSCLE-CELLS; PATTERN HAIR LOSS; ATP-GAMMA-S; EXTRACELLULAR ATP;

D O I：

10.1038/jid.2011.344

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

Adenosine 50-triphosphate and adenosine receptors have been identified in adult and fetal keratinocytes, fibroblasts, melanocytes, mast cells, Langerhans cells, and Meissner's corpuscles, as well as in hair follicles, sweat glands, and smooth muscle and endothelial cells of skin vessels. Purinergic signaling is involved in skin pathology, including inflammation, wound healing, pain, psoriasis, scleroderma, warts, and skin cancer.

引用

页码：526 / 546

页数：21

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