Microwave-induced one-pot synthesis of 4-[3-(aryl)-1,2,4-oxadiazol-5-yl]-butan-2-ones under solvent free conditions

被引：36

作者：

de Freitas, Juclelton Jose R.

de Freitas, Juliano Carlo R.

da Silva, Ladjane P.

de Freitas, Joao R. ^{[1
]}

Kimura, Gisele Y. V.

Srivastava, Rajendra M.

机构：

[1] Univ Fed Pernambuco, Dept Quim Fundamental, BR-50074054 Recife, PE, Brazil

[2] Univ Fed Rural Pernambuco, Unidade Acad Garanhuns, Recife, PE, Brazil

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 35期

关键词：

D O I：

10.1016/j.tetlet.2007.06.116

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 4-[3-(aryl)-1,2,4-oxadiazol-5-yl]-butan-2-ones (5a-I) from methyl levulinate (4) and arylamidoximes (1a-I) is described. The reaction was carried out in a microwave oven without any solvent in much shorter time and in yields comparable with conventional heating. (C) 2007 Elsevier Ltd. All rights reserved.

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页码：6195 / 6198

页数：4

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