Quantitative HPLC analysis of withanolides in Withania somnifera

被引:115
作者
Ganzera, M [1 ]
Choudhary, MI
Khan, IA
机构
[1] Univ Innsbruck, Inst Pharm, Dept Pharmacognosy, A-6020 Innsbruck, Austria
[2] Univ Mississippi, Inst Pharmaceut Sci, Natl Ctr Nat Prod Res, University, MS 38677 USA
[3] Univ Karachi, HEJ Res Inst Chem, Karachi 75270, Pakistan
[4] Univ Mississippi, Sch Pharm, Dept Pharmacognosy, University, MS 38677 USA
基金
美国农业部;
关键词
Withania somnifera; Ashwaghanda; withanolides; HPLC;
D O I
10.1016/S0367-326X(02)00325-8
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
One of the most widely used herbs in Ayurvedic medicine is Ashwaghanda, Withania somnifera, a shrub commonly found on the Indian subcontinent. As this plant is increasingly becoming a popular adaptogenic in the western world, analytical methods for its identification and quality control are in demand. Thus, a HPLC method for the determination of withaferin A and withanolide D was developed. The system was successfully used to investigate the presence of the markers in different W somnifera plant parts as well as to analyze their content in market products. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:68 / 76
页数:9
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