PROlocalizer: integrated web service for protein subcellular localization prediction

被引：27

作者：

Laurila, Kirsti ^{[1
,2
]}

Vihinen, Mauno ^{[1
,3
]}

机构：

[1] Univ Tampere, Inst Med Technol, Tampere 33014, Finland

[2] Tampere Univ Technol, Dept Signal Proc, FIN-33101 Tampere, Finland

[3] Tampere Univ Hosp, Ctr Sci, Tampere 33520, Finland

来源：

AMINO ACIDS | 2011年 / 40卷 / 03期

关键词：

Protein localization prediction; Cell compartments; Mutations; Disease-causing mutations; Prediction method; PEROXISOMAL TARGETING SIGNAL-1; TOPOLOGY; SITES; PSORT;

D O I：

10.1007/s00726-010-0724-y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Subcellular localization is an important protein property, which is related to function, interactions and other features. As experimental determination of the localization can be tedious, especially for large numbers of proteins, a number of prediction tools have been developed. We developed the PROlocalizer service that integrates 11 individual methods to predict altogether 12 localizations for animal proteins. The method allows the submission of a number of proteins and mutations and generates a detailed informative document of the prediction and obtained results. PROlocalizer is available at http://bioinf.uta.fi/PROlocalizer/.

引用

页码：975 / 980

页数：6

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