RETRACTED: Can fresh embryo transfers be replaced by cryopreserved-thawed embryo transfers in assisted reproductive cycles? A randomized controlled trial (Retracted article. See vol. 30, pg. 1245, 2013)

被引：97

作者：

Aflatoonian, Abbas ^{[1
]}

Oskouian, Homa ^{[1
]}

Ahmadi, Shahnaz ^{[1
]}

Oskouian, Leila ^{[1
]}

机构：

[1] Shahid Sadoughi Univ Med Sci, Dept Obstet & Gynecol, Res & Clin Ctr Infertil, Safaieh 8916877391, Yazd, Iran

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2010年 / 27卷 / 07期

关键词：

Endometrial receptivity; Fresh embryo transfer; Frozen-thawed embryo transfer; Ongoing pregnancy; Vitrification; OVARIAN HYPERSTIMULATION SYNDROME; HIGHLY EFFICIENT VITRIFICATION; HUMAN CHORIONIC-GONADOTROPIN; LIQUID-NITROGEN; HUMAN OOCYTES; ENDOMETRIAL RECEPTIVITY; INVITRO FERTILIZATION; PRONUCLEAR OOCYTES; STIMULATED CYCLES; IMPLANTATION;

D O I：

10.1007/s10815-010-9412-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学];

摘要：

Controlled ovarian hyperstimulation has been shown to advance endometrial maturation and adversely affects implantation in ART. It has been reported that there is a better embryo-endometrium synchrony in frozen-thawed embryo transfer cycles than fresh embryo transfer cycles. The objective of this study was to compare ongoing pregnancy rates between fresh ET and FET cycles. In an open prospective, controlled study, the patients who were classified as high responders, were randomized to either fresh ET or FET. The embryos in FET group were cryopreserved with vitrification by Cryotop method. A total of 374 patients were included, 187 of which were randomized to FET and 187 to fresh ET. There were 39% (n = 73) ongoing pregnancy in FET group compared with 27.8% (n = 52) in fresh ET group[odds ratio = 1.66;95% confidence interval = 1.07-2.56; p = 0.02]. FETs can be performed instead of fresh ETs to improve the outcome of ART in highly selected patients.

引用

页码：357 / 363

页数：7

共 32 条

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