Gene transcription in HIV infection

被引：29

作者：

Wu, YT ^{[1
]}

Marsh, JW ^{[1
]}

机构：

[1] NIMH, Mol Biol Lab, Bethesda, MD 20892 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 11期

关键词：

HIV; transcription; Tat; Rev; LTR;

D O I：

10.1016/S1286-4579(03)00187-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Transcription from the HIV genome is regulated by the 5' long-terminal-repeat viral promoter as well as regulatory proteins, especially Tat and Rev. Both the promoter activity and the function of regulatory proteins require the activity of cellular components, thus the virus remains highly dependent on the metabolic state of the cell. HIV also possesses the unusual capacity to transcribe from non-integrated DNA. Published by Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：1023 / 1027

页数：5

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