A short route to nucleoside diphosphate activated D- and L-hexoses

被引：14

作者：

Ernst, C ^{[1
]}

Klaffke, W ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 16期

关键词：

carbohydrates; nucleoside diphosphate sugars; Leloir-transferase donors; 1,2-anhydride;

D O I：

10.1016/S0040-4039(01)00352-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Leloir transferases utilise nucleoside diphosphate sugars, which are notoriously difficult to synthesise and handle. Starting off from D- or L-configurated glycals, a facile synthesis of nucleotide sugars by epoxidation and direct coupling with uridine diphosphate is described. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：2973 / 2975

页数：3

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