CART peptides: Modulators of mesolimbic dopamine, feeding, and stress

被引:34
作者
Dominguez, G
Vicentic, A
Del Giudice, EM
Jaworski, J
Hunter, RG
Kuhar, MJ
机构
[1] Emory Univ, Yerkes Natl Primate Res Ctr, Div Neurosci, Atlanta, GA 30329 USA
[2] Univ Naples 2, Dept Pediat, I-80138 Naples, Italy
来源
CURRENT STATUS OF DRUG DEPENDENCE / ABUSE STUDIES: CELLULAR AND MOLECULAR MECHANISMS OF DRUGS OF ABUSE AND NEUROTOXICITY | 2004年 / 1025卷
关键词
feeding; stress; satiety; body weight; reward;
D O I
10.1196/annals.1316.044
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
CART peptides have been shown to be peptide neurotransmitters and endocrine factors in a series of cumulative studies over the past eight years or so. This brief review touches on three aspects of CART: CART as a mediator or modulator of mesolimbic dopamine, CART's regulation by glucocorticoids, and CART as a regulator of feeding, satiety, and body weight. There have been several recent reviews and publications on various aspects of CART peptides. These aspects include the sequence and numbering of the peptides, and their structure, processing, and roles in various physiologic processes.
引用
收藏
页码:363 / 369
页数:7
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