A rhodamine-based fluorescent probe containing a Se-N bond for detecting thiols and its application in living cells

被引：402

作者：

Tang, Bo ^{[1
]}

Xing, Yanlong

Li, Ping

Zhang, Ning

Yu, Fabiao

Yang, Guiwen

机构：

[1] Shandong Normal Univ, Coll Med, Engn Res Ctr Pesticide & Med Intermediate, Minist Educ, Jinan 250014, Peoples R China

[2] Shandong Normal Univ, Coll Life Sci, Jinan 250014, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 38期

关键词：

D O I：

10.1021/ja072572q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we report a new rhodamine-based fluorescent probe containing a selenium-nitrogen bond for detecting thiols based on the nucleophilic substitution of sulfhydryl. The probe was successfully applied to the imaging of thiols in both HL-7702 cells and HepG2 cells with high sensitivity and selectivity.

引用

页码：11666 / +

页数：3

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