Combinatorial rosamine library and application to in vivo glutathione probe

被引：203

作者：

Ahn, Young-Hoon ^{[1
]}

Lee, Jun-Seok ^{[1
]}

Chang, Young-Tae ^{[1
]}

机构：

[1] NYU, Dept Chem, New York, NY 10003 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 15期

关键词：

D O I：

10.1021/ja068230m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Combinatorial approach on fluorescent rosamine library was developed using solid-phase chemistry. A highly selective library member (H22) toward reduced glutathione (GSH) was discovered, demonstrating the capability of in vivo GSH level sensing in live cells.

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页码：4510 / +

页数：3

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