Microwave-assisted functionalization of bromo-fluorescein and bromorhodamine derivatives

被引：34

作者：

Han, JW ^{[1
]}

Castro, JC ^{[1
]}

Burgess, K ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 52期

基金：

美国国家卫生研究院;

关键词：

fluorescent labels; microwave acceleration of reactions; borylation; Suzuki coupling; Sonogashira coupling;

D O I：

10.1016/j.tetlet.2003.10.063

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The overall goal of this project was to develop methodologies that would allow organometallic couplings of fluorescein and rhodamine derivatives. Consequently, borylation, Suzuki, and Sonogashira reactions of fragments derived from compounds 1 and 2 were investigated. Conventional and microwave heating were compared throughout the study. (C) 2003 Elsevier Ltd. All rights reserved.

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页码：9359 / 9362

页数：4

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