AVIS: AJAX viewer of interactive signaling networks

被引：19

作者：

Berger, Seth I. ^{[1
]}

Iyengar, Ravi ^{[1
]}

Ma'ayan, Avi ^{[1
]}

机构：

[1] CUNY Mt Sinai Sch Med, Dept Pharmacol & Syst Therapeut, New York, NY 10029 USA

来源：

BIOINFORMATICS | 2007年 / 23卷 / 20期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/bioinformatics/btm444

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: Increasing complexity of cell signaling network maps requires sophisticated visualization technologies. Simple web-based visualization tools can allow for improved data presentation and collaboration. Researchers studying cell signaling would benefit from having the ability to embed dynamic cell signaling maps in web pages. AVIS is a Google gadget compatible web-based viewer of interactive cell signaling networks. AVIS is an implementation of AJAX (Asynchronous JavaScript with XML) with the usage of the libraries GraphViz, ImageMagic (PerlMagic) and overLib. AVIS provides web-based visualization of text-based signaling networks with dynamical zooming, panning and linking capabilities. AVIS is a cross-platform web-based tool that can be used to visualize network maps as embedded objects in any web page. AVIS was implemented for visualization of PathwayGenerator, a tool that displays over 4000 automatically generated mammalian cell signaling maps; NodeNeighborhood a tool to visualize first and second interacting neighbors of yeast and mammalian proteins; and for Genes2Networks, a tool to connect lists of genes and protein using background protein interaction networks.

引用

页码：2803 / 2805

页数：3

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