Double reductive cyclization: a facile synthesis of the indoloquinoline alkaloid cryptotackieine

被引：46

作者：

Parvatkar, P. T.

Parameswaran, P. S. ^{[1
]}

Tilve, S. G.

机构：

[1] Natl Inst Oceanog, Panaji 403207, Goa, India

[2] Goa Univ, Dept Chem, Taleigao Plateau 403206, Goa, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 44期

关键词：

indoloquinoline alkaloid; Perkin reaction; cryptotackicieine; neocryptolepine; tandem; reductive cyclization;

D O I：

10.1016/j.tetlet.2007.08.126

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthesis of the indoloquinoline alkaloid cryptotackieine, isolated from Cryptolepis sanguinolenta, is described which involves a Perkin reaction, a tandem double reduction-double cyclization reaction followed by regioselective methylation at the quinoline nitrogen. (C) 2007 Elsevier Ltd. All rights reserved.

引用

收藏

页码：7870 / 7872

页数：3

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