Drug sensitivity and environmental adaptation of mycobacterial cell wall components

被引：73

作者：

Barry, CE ^{[1
]}

Mdluli, K ^{[1
]}

机构：

[1] NIAID,TB RES UNIT,INTRACELLULAR PARASITES LAB,ROCKY MT LABS,HAMILTON,MT 59840

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 07期

关键词：

D O I：

10.1016/0966-842X(96)10031-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The intrinsic resistance of many mycobacterial species to chemotherapy is largely attributable to their impermeable cell wall. The composition of the cell wall of a particular species appears to be influenced by the environmental niche that the species occupies. The complex regulatory and biosynthetic pathways involved in cell wall biosynthesis and construction offer useful chemotherapeutic targets against mycobacteria.

引用

页码：275 / 281

页数：7

共 58 条

[1] MUTATIONS IN THE CATALASE-PEROXIDASE GENE FROM ISONIAZID-RESISTANT MYCOBACTERIUM-TUBERCULOSIS ISOLATES [J].

ALTAMIRANO, M ;

MAROSTENMAKI, J ;

WONG, A ;

FITZGERALD, M ;

BLACK, WA ;

SMITH, JA .

JOURNAL OF INFECTIOUS DISEASES, 1994, 169 (05) :1162-1165

[2] THERMALLY ADAPTIVE-CHANGES OF MYCOLIC ACIDS IN MYCOBACTERIUM-SMEGMATIS [J].

BABA, T ;

KANEDA, K ;

KUSUNOSE, E ;

KUSUNOSE, M ;

YANO, I .

JOURNAL OF BIOCHEMISTRY, 1989, 106 (01) :81-86

[3]

BANNERJEE A, 1994, SCIENCE, V263, P227

[4]

BARROW WW, 1991, RES MICROBIOL, V142, P419

[5]

Besra Gurdyal S., 1994, P285

[6]

Brennan P., 1988, MICROBIAL LIPIDS, V1, P203

[7] THE ENVELOPE OF MYCOBACTERIA [J].

BRENNAN, PJ ;

NIKAIDO, H .

ANNUAL REVIEW OF BIOCHEMISTRY, 1995, 64 :29-63

[8]

CHATTERJEE D, 1992, J BIOL CHEM, V267, P6228

[9]

Connell Nancy D., 1994, P333

[10]

DAFFE M, 1990, J BIOL CHEM, V265, P6734

← 1 2 3 4 5 6 →