Gamma-hydroxybutyrate overdose and physostigmine: Teaching new tricks to an old drug?

被引:17
作者
Caldicott, DGE [1 ]
Kuhn, M [1 ]
机构
[1] Royal Adelaide Hosp, Emergency Dept, Adelaide, SA 5000, Australia
关键词
D O I
10.1067/mem.2001.111642
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Gamma-hydroxybutyrate was introduced as an anesthetic agent in the 1960s and is still used in some countries, despite recognized disadvantages. More recently, it has emerged as a popular recreational drug. We report 3 cases of gamma-hydroxybutyrale overdose, the effects of which were reversed by the administration of low-dose intravenous physostigmine. The origins of this regimen and the case for physostigmine as a potential antidote are described.
引用
收藏
页码:99 / 102
页数:4
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