Gamma-hydroxybutyrate overdose and physostigmine: Teaching new tricks to an old drug?

被引：17

作者：

Caldicott, DGE ^{[1
]}

Kuhn, M ^{[1
]}

机构：

[1] Royal Adelaide Hosp, Emergency Dept, Adelaide, SA 5000, Australia

来源：

ANNALS OF EMERGENCY MEDICINE | 2001年 / 37卷 / 01期

关键词：

D O I：

10.1067/mem.2001.111642

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Gamma-hydroxybutyrate was introduced as an anesthetic agent in the 1960s and is still used in some countries, despite recognized disadvantages. More recently, it has emerged as a popular recreational drug. We report 3 cases of gamma-hydroxybutyrale overdose, the effects of which were reversed by the administration of low-dose intravenous physostigmine. The origins of this regimen and the case for physostigmine as a potential antidote are described.

引用

页码：99 / 102

页数：4

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