Gating of GIRK channels: Details of an intricate, membrane-delimited signaling complex

被引：90

作者：

Sadja, R ^{[1
]}

Alagem, N ^{[1
]}

Reuveny, E ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel

来源：

NEURON | 2003年 / 39卷 / 01期

关键词：

D O I：

10.1016/S0896-6273(03)00402-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

G protein-coupled inwardly rectifying potassium channels (GIRK/Kir3) are important elements in controlling cellular excitability. In recent years, tremendous progress has been made toward understanding various components involved in channel activation, modulation, and signaling specificity. In this review, we summarize these recent findings and attempt to put them in context with recently available structural data.

引用

页码：9 / 12

页数：4

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