TLR-CD40 cross-talk in anti-leishmanial immune response

被引:9
作者
Chandel, Himanshu Singh [1 ]
Pandey, Surya Prakash [1 ]
Roy, Sayoni [1 ]
Doyen, Noelle [2 ]
Saha, Bhaskar [1 ]
机构
[1] Natl Ctr Cell Sci, Pune, Maharashtra, India
[2] Inst Pasteur, Paris, France
关键词
Toll-like receptors; PAMPs; CD40; Leishmania; immunomodulation; macrophages; dendritic cells; co-stimulatory molecules; TOLL-LIKE RECEPTOR-2; MHC CLASS-II; DENDRITIC CELLS; T-CELLS; PROTEIN-KINASE; CD40; EXPRESSION; INTERLEUKIN-12; ACTIVATION; TLR;
D O I
10.3389/fimmu.2014.00220
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
引用
收藏
页数:5
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共 49 条
[1]
TLR9-Dependent Activation of Dendritic Cells by DNA from Leishmania major Favors Th1 Cell Development and the Resolution of Lesions [J].
Abou Fakher, Faihaa Hkima ;
Rachinel, Nicolas ;
Klimczak, Martine ;
Louis, Jacques ;
Doyen, Noelle .
JOURNAL OF IMMUNOLOGY, 2009, 182 (03) :1386-1396
[2]
Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN [J].
Ahonen, CL ;
Doxsee, CL ;
McGurran, SM ;
Riter, TR ;
Wade, WF ;
Barth, RJ ;
Vasilakos, JP ;
Noelle, RJ ;
Kedl, RM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 199 (06) :775-784
[3]
Pathogen recognition and innate immunity [J].
Akira, S ;
Uematsu, S ;
Takeuchi, O .
CELL, 2006, 124 (04) :783-801
[4]
Arabinosylated Lipoarabinomannan-Mediated Protection in Visceral Leishmaniasis through Up-Regulation of Toll-Like Receptor 2 Signaling: An Immunoprophylactic Approach [J].
Bhattacharya, Parna ;
Bhattacharjee, Surajit ;
Gupta, Gaurav ;
Majumder, Saikat ;
Adhikari, Anupam ;
Mukherjee, Asok ;
Majumdar, Suchandra Bhattacharyya ;
Saha, Bhaskar ;
Majumdar, Subrata .
JOURNAL OF INFECTIOUS DISEASES, 2010, 202 (01) :145-155
[5]
Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells [J].
Bix, M ;
Locksley, RM .
SCIENCE, 1998, 281 (5381) :1352-1354
[6]
Intracellular Toll-like Receptors [J].
Blasius, Amanda L. ;
Beutler, Bruce .
IMMUNITY, 2010, 32 (03) :305-315
[7]
The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products [J].
Bowie, A ;
O'Neill, LAJ .
JOURNAL OF LEUKOCYTE BIOLOGY, 2000, 67 (04) :508-514
[8]
CD4+ CD25+ T cells in skin lesions of patients with cutaneous leishmaniasis exhibit phenotypic and functional characteristics of natural regulatory T cells [J].
Campanelli, AP ;
Roselino, AM ;
Cavassani, KA ;
Pereira, MSF ;
Mortara, RA ;
Brodskyn, CI ;
Gonçalves, HS ;
Belkaid, Y ;
Barral-Netto, M ;
Barral, A ;
Silva, JS .
JOURNAL OF INFECTIOUS DISEASES, 2006, 193 (09) :1313-1322
[9]
Lysophosphatidylcholine Triggers TLR2-and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation [J].
Carneiro, Alan Brito ;
Ferreira Iaciura, Bruna Maria ;
Nohara, Lilian Lie ;
Lopes, Carla Duque ;
Cordero Veas, Esteban Mauricio ;
Mariano, Vania Sammartino ;
Bozza, Patricia Torres ;
Lopes, Ulisses Gazos ;
Atella, Georgia Correa ;
Almeida, Igor Correia ;
Cardoso Silva-Neto, Mario Alberto .
PLOS ONE, 2013, 8 (09)
[10]
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation [J].
Cella, M ;
Scheidegger, D ;
PalmerLehmann, K ;
Lane, P ;
Lanzavecchia, A ;
Alber, G .
JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (02) :747-752