Effect of spacers on the activity of soluble polymer supported catalysts for the asymmetric addition of diethylzinc to aldehydes

被引：37

作者：

Anyanwu, UK ^{[1
]}

Venkataraman, D ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(03)01588-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A chiral Zn(II)-salen complex tethered with poly(ethylene glycol) (PEG) was synthesized. This soluble polymer-supported complex was found to catalyze the asymmetric addition of diethylzinc to a series of aromatic aldehydes in good yields and with good enantiomeric ratio (er). The PEG-supported catalyst could be recycled and reused up to three times. The reactivity and selectivity of the catalyst was dependent on the nature of the linker between the polymer and the complex. (C) 2003 Elsevier Ltd. All rights reserved.

引用

收藏

页码：6445 / 6448

页数：4

相关论文

共 34 条

[1] Polymer-supported chiral Co(salen) complexes: Synthetic applications and mechanistic investigations in the hydrolytic kinetic resolution of terminal epoxides [J].

Annis, DA ;

Jacobsen, EN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (17) :4147-4154

[2] Synthesis of poly(ethylene glycol)-supported manganese porphyrins: efficient, recoverable and recyclable catalysts for epoxidation of alkenes [J].

Benaglia, M ;

Danelli, T ;

Pozzi, G .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2003, 1 (03) :454-456

[3] Poly(ethylene glycol)-supported tetrahydroxyphenyl porphyrin: A convenient, recyclable catalyst for photooxidation reactions [J].

Benaglia, M ;

Danelli, T ;

Fabris, F ;

Sperandio, D ;

Pozzi, G .

ORGANIC LETTERS, 2002, 4 (24) :4229-4232

[4] Using soluble polymers to recover catalysts and ligands [J].

Bergbreiter, DE .

CHEMICAL REVIEWS, 2002, 102 (10) :3345-3383

[5] Soluble polymer-supported catalysts containing azo dyes [J].

Bergbreiter, DE ;

Osburn, PL ;

Li, CM .

ORGANIC LETTERS, 2002, 4 (05) :737-740

[6] Functionalized hyperbranched grafts on polyethylene powder for support of Pd(0)-phosphine catalyst [J].

Bergbreiter, DE ;

Kippenberger, AM ;

Tao, GL .

CHEMICAL COMMUNICATIONS, 2002, (18) :2158-2159

[7] New methods for recovery of soluble polymer-bound reagents [J].

Bergbreiter, DE ;

Frels, J ;

Heuze, K .

REACTIVE & FUNCTIONAL POLYMERS, 2001, 49 (03) :249-254

[8]

Bolm C, 2002, ADV SYNTH CATAL, V344, P649, DOI 10.1002/1615-4169(200208)344:6/7<649::AID-ADSC649>3.0.CO

[9]

2-X

[10] Utilisation of homogeneous and supported chiral metal(salen) complexes in asymmetric catalysis [J].

Canali, L ;

Sherrington, DC .

CHEMICAL SOCIETY REVIEWS, 1999, 28 (02) :85-93

← 1 2 3 4 →