Physiological pathways regulating the activity of magnocellular neurosecretory cells

被引：243

作者：

Leng, G ^{[1
]}

Brown, CH ^{[1
]}

Russell, JA ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Med, Dept Physiol, Neuroendocrinol Lab, Edinburgh EH8 9AG, Midlothian, Scotland

来源：

PROGRESS IN NEUROBIOLOGY | 1999年 / 57卷 / 06期

关键词：

D O I：

10.1016/S0301-0082(98)00072-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Magnocellular oxytocin and vasopressin cells are among the most extensively studied neurons in the brain: their large size and high synthetic capacity, their discrete, homogeneous distribution and the anatomical separation of their terminals from their cell bodies, and the ability to determine their neuronal output readily by measurements of hormone concentration in the plasma, combine to make these systems amenable to a wide range of fundamental investigations While vasopressin cells have intrinsic burst-generating properties, oxytocin cells are organized within local pattern-generating networks. In this review we consider the role played by particular different pathways in the regulation of the activity of oxytocin and vasopressin cells. For both cell types, the effects of changes in the activity of synaptic input can be complex. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：625 / 655

页数：31

共 285 条

[41] DIRECT PATHWAY FROM NEURONS IN THE VENTROLATERAL MEDULLA RELAYING CARDIOVASCULAR AFFERENT INFORMATION TO THE SUPRAOPTIC NUCLEUS IN THE CAT [J].