Superpositioned dielectrophoresis for enhanced trapping efficiency

被引:40
作者
Aldaeus, F
Lin, Y
Roeraade, J [1 ]
Amberg, G
机构
[1] Royal Inst Technol, Dept Chem Analyt Chem, SE-10044 Stockholm, Sweden
[2] Royal Inst Technol, Dept Mech Fluid Mech, SE-10044 Stockholm, Sweden
关键词
alternating current electrokinetics; dielectrophoresis; Escherichia coli; field superposition; trajectory analysis;
D O I
10.1002/elps.200500068
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
One of the major applications for dielectrophoresis is selective trapping and fractionation of particles. If the surrounding medium is of low conductivity, the trapping force is high, but if the conductivity increases, the attraction decreases and may even become negative. However, high-conductivity media are essential when working with biological material such as living cells. In this paper, some basic calculations have been performed, and a model has been developed which employs both positive and negative dielectrophoresis in a channel with interdigitated electrodes. The finite element method was utilized to predict the trajectories of Escherichia coli bacteria in the superpositioned electrical fields. It is shown that a drastic improvement of trapping efficiency can be obtained in this way, when a high conductivity medium is employed.
引用
收藏
页码:4252 / 4259
页数:8
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