Emerging applications of multifunctional elastin-like recombinamers

被引:41
作者
Carlos Rodriguez-Cabello, J. [1 ]
Martin, Laura [1 ]
Girotti, Alessandra [1 ]
Garcia-Arevalo, Carmen [1 ]
Javier Arias, F. [1 ]
Alonso, Matilde [1 ]
机构
[1] Univ Valladolid, CIBER BBN, Bioforge Grp, E-47011 Valladolid, Spain
关键词
drug delivery; elastin-like recombinamers; nanodevices; protein purification; surface engineering; tissue engineering; EXTRACELLULAR-MATRIX PROTEINS; POLYPEPTIDE-DOXORUBICIN CONJUGATE; INVERSE TEMPERATURE TRANSITION; CELL-ADHESION; DRUG-DELIVERY; CROSS-LINKING; BIOMEDICAL APPLICATIONS; SOLID TUMORS; POLYMERS; DESIGN;
D O I
10.2217/NNM.10.141
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Elastin-like recombinamers have grown in popularity in the field of protein-inspired biomimetic materials and have found widespread use in biomedical applications. Modern genetic-engineering techniques have allowed the design of multifunctional materials with an extraordinary control over their architecture and physicochemical properties, such as stimuli-responsiveness, monodispersity, biocompatibility or self-assembly, amongst others. Indeed, these materials are playing an increasingly important role in a diverse range of applications, such as drug delivery, tissue engineering and 'smart' systems. Herein, we review some of the most interesting examples of recent advances, and progressive applications of elastin-like recombinamers in biomaterial and nano-engineering sciences in recent years.
引用
收藏
页码:111 / 122
页数:12
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