Elevated frequencies of natural killer T lymphocytes in myasthenia gravis

被引：17

作者：

Reinhardt, C

Melms, A

机构：

[1] Max Planck Inst Psychiat, D-80804 Munich, Germany

[2] Univ Tubingen, Dept Neurol, D-7400 Tubingen, Germany

来源：

NEUROLOGY | 1999年 / 52卷 / 07期

关键词：

D O I：

10.1212/WNL.52.7.1485

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

T lymphocytes are considered to exert a regulatory function in the development of antiacetylcholine receptor antibodies, but no clear T-cell alterations in patients with myasthenia gravis (MG) have yet been found. The authors report a significant increase of recently identified natural killer T lymphocytes expressing T-cell receptor V alpha 24. A possible role in disease initiation or maintenance is suggested by the observed strong synthesis of interferon-gamma as well as of interleukin 4.

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页码：1485 / 1487

页数：3

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