Prevalence of hepatitis C in prisons: WASH-C surveillance linked to self-reported risk behaviours

被引:47
作者
Gore, SM
Bird, AG
Cameron, SO
Hutchinson, SJ
Burns, SM
Goldberg, DJ
机构
[1] Inst Publ Hlth, MRC, Biostat Unit, Cambridge CB2 2SR, England
[2] John Radcliffe Hosp, Dept Immunol, Oxford OX3 9DU, England
[3] Reg Virus Lab, Glasgow, Lanark, Scotland
[4] MRC, BIAS, Edinburgh, Midlothian, Scotland
[5] Reg Virus Lab, Edinburgh, Midlothian, Scotland
[6] Scottish Ctr Infect & Environm Hlth, Glasgow, Lanark, Scotland
来源
QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS | 1999年 / 92卷 / 01期
关键词
D O I
10.1093/qjmed/92.1.25
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We used cross-sectional willing anonymous salivary hepatitis C (WASH-C) surveillance linked to self-completed risk-factor questionnaires to estimate the prevalence of salivary hepatitis C antibodies (HepCAbS) in five Scottish prisons from 1994 to 1996. Of 2121 available inmates, 1864 (88%) participated and 1532/1864 (82%) stored samples were suitable for testing. Overall 311/1532 (20.3%, prevalence 95%Cl 18.3-22.3%) were HepCAbS-positive: 265/536 (49%, 95%Cl 45-54%) injector-inmates but only 27/899 (3%, 95%Cl 2-4%) non-injector-inmates. Among injectors, HepCAbS positivity was only slightly higher (p=0.03) in those who had injected inside prison (53%, 162/305) than in those who had not (44%, 98/224). Those who began injecting in 1992-96 were much less likely to be HepCAbS-positive than those who started pre-1992 (31%, 35/114 vs. 55%, 230/422; p<0.001). Even with injectors who began in 1992-96 but had never injected inside prison, the prevalence of hepatitis C carriage was 17/63 (95%Cl 16-38%). The prevalence and potential transmissibility of hepatitis C in injector-inmates are both high. Promoting 'off injecting' before 'off drugs' (both inside and outside prison), methadone prescription during short incarcerations, alternatives to prison, and support of HepCAbS-positive inmates in becoming eligible for treatment, all warrant urgent consideration.
引用
收藏
页码:25 / 32
页数:8
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